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Product Description
anti- SPHK1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene..
Immunogen: sphingosine kinase 1
Synonyms: SPHK, SPK
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded rat liver using FNab08173(SPHK1 antibody) at dilution of 1:200
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab08173(SPHK1 antibody) at dilution of 1:1000
Gene ID: 8877
Research Area: Metabolism
Uniprot ID: Q9NYA1
