anti- SPTLC1 antibody

Product Description

anti- SPTLC1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13..

Immunogen: serine palmitoyltransferase, long chain base subunit 1

Synonyms: HSAN, HSAN1, HSN1, LBC1, LCB 1, LCB1, Serine palmitoyltransferase 1, SPT 1, SPT1, SPTI, SPTLC1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human kidney using FNab08206(SPTLC1 antibody) at dilution of 1:100

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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab08206(SPTLC1 antibody) at dilution of 1:1000

Gene ID: 10558

Research Area: Metabolism

Uniprot ID: O15269