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Product Description
anti- STAM antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body(MVBs) when complexed with HGS(ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes..
Immunogen: signal transducing adaptor molecule(SH3 domain and ITAM motif) 1
Synonyms: STAM1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IF, IP
Recommended dilution:
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08283(STAM antibody) at dilution of 1:1500
Gene ID: 8027
Research Area: Metabolism
Uniprot ID: Q92783
