Product Description
anti- STAM2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body(MVBs) when complexed with HGS(ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes(By similarity)..
Immunogen: signal transducing adaptor molecule(SH3 domain and ITAM motif) 2
Synonyms: HBP
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IP
Recommended dilution:
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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08284(STAM2 antibody) at dilution of 1:1000
Gene ID: 10254
Research Area: Metabolism
Uniprot ID: O75886