anti- STT3A antibody

Product Description

anti- STT3A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Catalytic subunit of the N-oligosaccharyl transferase(OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum(ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A..

Immunogen: STT3, subunit of the oligosaccharyltransferase complex, homolog A

Synonyms: B5, Integral membrane protein 1, ITM1, STT3 A, STT3A, TMC, Transmembrane protein TMC

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB, IF

Recommended dilution: WB: 1:1000-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab08355(STT3A antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of HEK-293 cells using FNab08355 (STT3A antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08355(STT3A Antibody) at dilution of 1:2000

Gene ID: 3703

Research Area: Metabolism

Uniprot ID: P46977