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Product Description
anti- TCEB1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified..
Immunogen: transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab08548(TCEB1 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08548(TCEB1 antibody) at dilution of 1:1000
Gene ID: 6921
Research Area: Metabolism
Uniprot ID: Q15369
