anti- TCEB2 antibody

Product Description

anti- TCEB2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13..

Immunogen: transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)

Synonyms:

Reactivity: Human

Tested Application: ELISA, WB, IHC, IP

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:20 - 1:50

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab08549(TCEB2 antibody) at dilution of 1:100

Image 2: .

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab08549(TCEB2 antibody) at dilution of 1:1000

Gene ID: 6923

Research Area: Metabolism

Uniprot ID: Q15370