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Product Description
anti- TDP1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate..
Immunogen: tyrosyl-DNA phosphodiesterase 1
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IP
Recommended dilution:
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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab08572(TDP1 antibody) at dilution of 1:1000
Gene ID: 55775
Research Area: Metabolism
Uniprot ID: Q9NUW8
