Product Description
anti- TELO2 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation..
Immunogen: TEL2, telomere maintenance 2, homolog(S. cerevisiae)
Synonyms: KIAA0683
Reactivity: Human
Tested Application: ELISA, IHC, IF, IP, WB
Recommended dilution: WB: 1:1000-1:4000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Image 1: Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab08592(TELO2 Antibody) at dilution of 1:200
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Image 4: A431 cells were subjected to SDS PAGE followed by western blot with FNab08592(TELO2 antibody) at dilution of 1:500
Gene ID: 9894
Research Area: Metabolism
Uniprot ID: Q9Y4R8