anti- TFE3 antibody

Product Description

anti- TFE3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site..

Immunogen: transcription factor binding to IGHM enhancer 3

Synonyms: bHLHe33, RCCP2, TFE3, TFEA, Transcription factor E3

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IP,IHC

Recommended dilution: WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using FNab08626(TFE3 Antibody) at dilution of 1:200

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Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab08626(TFE3 antibody) at dilution of 1:1000

Gene ID: 7030

Research Area: Metabolism

Uniprot ID: P19532