anti- TGF-beta 3 antibody

Product Description

anti- TGF-beta 3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1..

Immunogen: transforming growth factor, beta 3

Synonyms: ARVD, ARVD1, LDS5, RNHF, TGF-beta3

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded mouse ovary using FNab08640(TGFB3 antibody) at dilution of 1:100

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Image 4: K-937 cells were subjected to SDS PAGE followed by western blot with FNab08640(TGFB3 antibody) at dilution of 1:1000

Gene ID: 7043

Research Area: Metabolism

Uniprot ID: P10600