Product Description
anti- Tie2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known..
Immunogen: TEK tyrosine kinase, endothelial
Synonyms: CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Image 1: Immunohistochemistry of paraffin-embedded human lung cancer using FNab08690(Tie2 antibody) at dilution of 1:100
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Image 4: mouse kidney were subjected to SDS PAGE followed by western blot with FNab08690(Tie2 antibody) at dilution of 1:1000
Gene ID: 7010
Research Area: Metabolism
Uniprot ID: Q02763