anti- TNFSF12 antibody

Product Description

anti- TNFSF12 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13..

Immunogen: tumor necrosis factor (ligand) superfamily, member 12

Synonyms: APO3L, DR3LG

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded mouse testis using FNab08827(TNFSF12 Antibody) at dilution of 1:100

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Image 4: SW620 cells were subjected to SDS PAGE followed by western blot with FNab08827(TNFSF12 Antibody) at dilution of 1:1000

Gene ID: 8742

Research Area: Metabolism

Uniprot ID: O43508