anti- TNFSF13B antibody

Product Description

anti- TNFSF13B antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands-2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor(BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Isoform 2 seems to inhibit isoform 1 secretion and bioactivity. Isoform 3: Acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-cell diseases. The presence of Delta4BAFF is essential for soluble BAFF release by IFNG/IFN-gamma-stimulated monocytes and for B-cell survival. It can directly or indirectly regulate the differential expression of a large number of genes involved in the innate immune response and the regulation of apoptosis..

Immunogen: tumor necrosis factor(ligand) superfamily, member 13b

Synonyms: BAFF, BLYS, TALL1, TNFSF20, ZTNF4

Reactivity: Human, Mouse

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08829(TNFSF13B antibody) at dilution of 1:1000

Gene ID: 10673

Research Area: Metabolism

Uniprot ID: Q9Y275