anti- TNPO2 antibody

Product Description

anti- TNPO2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity)..

Immunogen: transportin 2

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF

Recommended dilution:

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Image 4: fetal human brain tissue were subjected to SDS PAGE followed by western blot with FNab08844(TNPO2 Antibody) at dilution of 1:1000

Gene ID: 30000

Research Area: Metabolism

Uniprot ID: O14787