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Product Description
anti- TRADD antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A(By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B..
Immunogen: TNFRSF1A-associated via death domain
Synonyms: Hs.89862, TRADD
Reactivity: Human, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:200 - 1:2000; IHC: 1:50 - 1:500
Image 1: Immunohistochemistry of paraffin-embedded rat liver tissue slide using FNab08915( TRADD antibody at dilution of 1:200
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08915( TRADD Antibody) at dilution of 1:1000
Gene ID: 8717
Research Area: Metabolism
Uniprot ID: Q15628
