anti- TRIB3 antibody

Product Description

anti- TRIB3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA..

Immunogen: tribbles homolog 3(Drosophila)

Synonyms: C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IP

Recommended dilution: WB: 1:500-1:5000; IP: 1:200-1:2000

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Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab08966(TRIB3 antibody) at dilution of 1:600

Gene ID: 57761

Research Area: Metabolism

Uniprot ID: Q96RU7