anti- TRPV6 antibody

Product Description

anti- TRPV6 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine(PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin(By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification(PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating..

Immunogen: transient receptor potential cation channel, subfamily V, member 6

Synonyms: ABP/ZF, Calcium transport protein 1, CaT L, CaT like, CAT1, CATL, ECAC2, Epithelial calcium channel 2, HSA277909, LP6728, TRPV6, ZFAB

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IF, WB, IP

Recommended dilution: WB: 1:500-1:5000; IP: 1:200-1:1000; IF: 1:10-1:100

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Image 4: human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09030(TRPV6 Antibody) at dilution of 1:1000

Gene ID: 55503

Research Area: Metabolism

Uniprot ID: Q9H1D0