anti- TSG101 antibody

Product Description

anti- TSG101 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression..

Immunogen: tumor susceptibility gene 101

Synonyms: ESCRT I complex subunit TSG101, TSG10, TSG101, tumor susceptibility gene 101, VPS23

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab09040( TSG101 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09040(TSG101 antibody) at dilution of 1:1000

Gene ID: 7251

Research Area: Metabolism

Uniprot ID: Q99816