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Product Description
anti- TTRAP antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: TTRAP is a 5-prime tyrosyl-DNA phosphodiesterase that is required for efficient repair of topoisomerase II-induced DNA double-strand breaks. Thus it can remove lots of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, generating a free 5' phosphate to DNA. It also has 3'-tyrosyl DNA phophodiesterase activity, but not so efficient as TDP1. TTRAP functions as a negative regulator of ETS1 and inhibit nuclear factor-kappa-B activation..
Immunogen: TRAF and TNF receptor associated protein
Synonyms: 5 Tyr DNA phosphodiesterase, AD022, dJ30M3.3, EAP2, EAPII, ETS1 associated protein 2, ETS1 associated protein II, TDP2, TTRAP, Tyr DNA phosphodiesterase 2
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IP
Recommended dilution: WB: 1:500-1:5000; IP: 1:200-1:2000
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Image 4: human spleen tissue were subjected to SDS PAGE followed by western blot with FNab09098(TTRAP antibody) at dilution of 1:500
Research Area: Metabolism
Uniprot ID: O95551
