anti- UAP56 antibody

Product Description

anti- UAP56 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene..

Immunogen: HLA-B associated transcript 1

Synonyms: ATP dependent RNA helicase p47, BAT1, D6S81E, DDX39B, DEAD box protein UAP56, HLA B associated transcript 1, Spliceosome RNA helicase BAT1, UAP56

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab09142(BAT1 antibody) at dilution of 1:100

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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09142(BAT1 antibody) at dilution of 1:1000

Gene ID: 7919

Research Area: Metabolism

Uniprot ID: Q13838