Product Description
anti- UBASH3A-Specific antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: UBASH3A gene encodes ubiquitin-associated and SH3 domain-containing protein A(UBASH3A) also known as T-cell ubiquitin ligand 1(TULA1) which is one of two family members belonging to the T-cell ubiquitin ligand(TULA) family. UBASH3A gene expression is limited to only a few tissues, with its highest expression in spleen, peripheral blood leukocytes, and bone marrow. UBASH3A protein is associated with c-Cbl and ubiquitylated proteins and has been implicated in the regulation of signaling mediated by protein-tyrosine kinases oth family members can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells via its interaction with apoptosis-inducing factor(AIF). This antibody is UBASH3A-specific..
Immunogen: ubiquitin associated and SH3 domain containing, A
Synonyms: Cbl interacting protein 4, CLIP4, STS 2, STS2, T cell ubiquitin ligand, TULA, UBASH3A
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IF, IP
Recommended dilution: WB: 1:200-1:2000; IF: 1:10-1:100?IP: 1:200-1:2000
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Image 4: human spleen tissue were subjected to SDS PAGE followed by western blot with FNab09150(UBASH3A-Specific antibody) at dilution of 1:400
Research Area: Metabolism
Uniprot ID: P57075