anti- UBE2C antibody

Product Description

anti- UBE2C antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit..

Immunogen: ubiquitin-conjugating enzyme E2C

Synonyms: DJ447F3.2, UBCH10, UBE2C, Ubiquitin carrier protein C, Ubiquitin protein ligase C

Reactivity: Human

Tested Application: ELISA, IF, IHC, WB

Recommended dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer slide using FNab09166(UBE2C Antibody) at dilution of 1:50

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09166(UBE2C Antibody) at dilution of 1:1000

Gene ID: 11065

Research Area: Metabolism

Uniprot ID: O00762