anti- UCHL1/PGP9.5 antibody

Product Description

anti- UCHL1/PGP9.5 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm(PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene(PMID:15048890)..

Immunogen: ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase)

Synonyms: Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uch L1, UCHL1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recommended dilution: WB: 1:500-1:5000; IHC?1:100-1:500; IP: 1:1000-1:5000

Image 1: Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab09218(UCHL1/PGP9.5) antibody at dilution of 1:200

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Image 4: A549 cells were subjected to SDS PAGE followed by western blot with FNab09218(UCHL1 antibody) at dilution of 1:3000

Gene ID: 7345

Research Area: Metabolism

Uniprot ID: P09936