Product Description
anti- UNC13A/Munc13-1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A..
Immunogen: unc-13 homolog A(C. elegans)
Synonyms: KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A(C. elegans), UNC13A
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:5000; IP: 1?200-1?2000
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Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab09255(UNC13A antibody) at dilution of 1:300
Research Area: Metabolism
Uniprot ID: Q9UPW8