anti- URM1 antibody

Product Description

anti- URM1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated(-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein(UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates..

Immunogen: ubiquitin related modifier 1 homolog(S. cerevisiae)

Synonyms: URM1, C9orf74

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:5000; IHC?1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human liver cancer using FNab09289(URM1 antibody) at dilution of 1:100

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Image 4: human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09289(URM1 antibody) at dilution of 1:1000

Gene ID: 81605

Research Area: Metabolism

Uniprot ID: Q9BTM9