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Product Description
anti- Uromodulin antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Uromodulin, also known as THP(Tamm-Horsfall glycoprotein), is the most abundant protein excreted in the urine under physiological conditions. Uromodulin is synthesized by kidney and localizes in cells lining the ascending limb of Henle and distal convoluted tubule. Uromodulin has been linked to water/electrolyte balance and to kidney innate immunity. Also, studies in knockout mice demonstrated that it has a protective role against urinary tract infections and renal stone formation. Mutations in the gene encoding uromodulin lead to rare autosomal dominant diseases, collectively referred to as uromodulin-associated kidney diseases.(PMID: 21654721).
Immunogen: uromodulin
Synonyms: ADMCKD2, FJHN, HNFJ, MCKD2, THGP, THP, UMOD, uromodulin
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recommended dilution: WB: 1:200-1:2000; IHC: 1:20-1:500; IP: 1:200-1:2000
Image 1: Immunohistochemistry of paraffin-embedded human kidney using FNab09294(UMOD antibody) at dilution of 1:50
Image 2: .
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Image 4: human heart tissue were subjected to SDS PAGE followed by western blot with FNab09294(UMOD antibody) at dilution of 1:400
Research Area: Metabolism
Uniprot ID: P07911
