anti- USP11 antibody

Product Description

anti- USP11 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains(PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome(PubMed:12084015). Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains(in vitro)(PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation(PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks(PubMed:15314155, PubMed:20233726)..

Immunogen: ubiquitin specific peptidase 11

Synonyms: Deubiquitinating enzyme 11, Ubiquitin thiolesterase 11, UHX1, USP11

Reactivity: Human

Tested Application: ELISA, WB, IHC, IP

Recommended dilution: WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab09306(USP11 Antibody) at dilution of 1:50

Image 2: .

Image 3:

Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09306(USP11 antibody) at dilution of 1:1000

Gene ID: 8237

Research Area: Metabolism

Uniprot ID: P51784