anti- USP14 antibody

Product Description

anti- USP14 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation(ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions(NMJs)..

Immunogen: ubiquitin specific peptidase 14(tRNA-guanine transglycosylase)

Synonyms: Deubiquitinating enzyme 14, TGT, Ubiquitin thiolesterase 14, USP14

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, FC

Recommended dilution: WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100

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Image 4: mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab09310(USP14 antibody) at dilution of 1:300

Gene ID: 9097

Research Area: Metabolism

Uniprot ID: P54578