anti- USP16 antibody

Product Description

anti- USP16 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Specifically deubiquitinates 'Lys-120' of histone H2A(H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3(H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B-and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B..

Immunogen: ubiquitin specific peptidase 16

Synonyms: Deubiquitinating enzyme 16, Ubiquitin thiolesterase 16, UBP M, USP16

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recommended dilution: WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human kidney using FNab09312(USP16 antibody) at dilution of 1:100

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09312(USP16 antibody) at dilution of 1:1000

Gene ID: 10600

Research Area: Metabolism

Uniprot ID: Q9Y5T5