anti- USP34 antibody

Product Description

anti- USP34 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin(CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins..

Immunogen: ubiquitin specific peptidase 34

Synonyms: Deubiquitinating enzyme 34, FLJ43910, KIAA0570, KIAA0729, Ubiquitin thiolesterase 34, USP34

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:5000; IP: 1?200-1?2000; IHC: 1?20-1?200

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab09327(USP34 Antibody) at dilution of 1:50

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Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab09327(USP34 antibody) at dilution of 1:600

Gene ID: 9736

Research Area: Metabolism

Uniprot ID: Q70CQ2