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Product Description
anti- USP44 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome(APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex(also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B(H2BK120ub1) ubiquitination..
Immunogen: ubiquitin specific peptidase 44
Synonyms: Deubiquitinating enzyme 44, DKFZp434D0127, FLJ14528, Ubiquitin thiolesterase 44, USP44
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:5000
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Image 4: human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09334(USP44 antibody) at dilution of 1:500
Gene ID: 84101
Research Area: Metabolism
Uniprot ID: Q9H0E7
