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Product Description
anti- USP5 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition..
Immunogen: ubiquitin specific peptidase 5(isopeptidase T)
Synonyms: Deubiquitinating enzyme 5, Isopeptidase T, ISOT, Ubiquitin thiolesterase 5, USP5
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:5000
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09341(USP5 Antibody) at dilution of 1:1000
Gene ID: 8078
Research Area: Metabolism
Uniprot ID: P45974
