anti- USP9X antibody

Product Description

anti- USP9X antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'-and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration..

Immunogen: ubiquitin specific peptidase 9, X-linked

Synonyms: Deubiquitinating enzyme FAF X, DFFRX, FAF, FAM, Fat facets in mammals, hFAM, Ubiquitin thiolesterase FAF X, USP9, USP9X

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IHC, IP

Recommended dilution: WB: 1:500-1:5000; IF: 1:10-1:100; IHC: 1?20-1?200; IP: 1?200-1?2000

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using FNab09344(USP9X Antibody) at dilution of 1:50

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09344(USP9X antibody) at dilution of 1:500

Gene ID: 8239

Research Area: Metabolism

Uniprot ID: Q93008