anti- VDR antibody

Product Description

anti- VDR antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins..

Immunogen: vitamin D (1, 25- dihydroxyvitamin D3) receptor

Synonyms: NR1I1, VDR, Vitamin D3 receptor

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Image 1:

Image 2: .

Image 3:

Image 4: PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09390( VDR Antibody) at dilution of 1:1000

Gene ID: 7421

Research Area: Metabolism

Uniprot ID: P11473