anti- VEGFR-1/FLT-1 antibody

Product Description

anti- VEGFR-1/FLT-1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia..

Immunogen: fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)

Synonyms: FLT, FLT 1, FLT1, FLT-1, Fms like tyrosine kinase 1, FRT, sflt1, Tyrosine protein kinase FRT, VEGF receptor 1, VEGFR 1, VEGFR1, VEGFR-1

Reactivity: Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded mouse lung using FNab09393(VEGFR1, FLT1 antibody) at dilution of 1:100

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09393(VEGFR1, FLT1 antibody) at dilution of 1:1000

Gene ID: 2321

Research Area: Metabolism

Uniprot ID: P17948