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Product Description
anti- Vimentin antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha(TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10(124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level..
Immunogen: vimentin
Synonyms: FLJ36605, VIM, Vimentin
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:1000-1:10000; IHC: 1:20-1:2000; IF: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human renal cell carcinoma tissue slide using FNab09410(Vimentin Antibody) at dilution of 1:500.
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09410(Vimentin Antibody) at dilution of 1:2000
Research Area: Metabolism
Uniprot ID: P08670
