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Product Description
anti- VPS53 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor(TFRC) to the plasma membrane(PubMed:25799061)..
Immunogen: vacuolar protein sorting 53 homolog(S. cerevisiae)
Synonyms: FLJ10979, HCCS1, hVps53L, pp13624, VPS53
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:5000?IP: 1:200-1:2000
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Image 4: human liver tissue were subjected to SDS PAGE followed by western blot with FNab09448(VPS53 antibody) at dilution of 1:300
Gene ID: 55275
Research Area: Metabolism
Uniprot ID: Q5VIR6
