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Product Description
anti- WDFY3 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Required for selective autophagy(aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies(p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation..
Immunogen: WD repeat and FYVE domain containing 3
Synonyms: ALFY, Autophagy linked FYVE protein, KIAA0993, WDFY3, ZFYVE25
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC
Recommended dilution: IHC: 1:20-1:200
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Image 4: Immunohistochemical of paraffin-embedded human breast cancer using FNab09479(WDFY3 antibody) at dilution of 1:50
Gene ID: 23001
Research Area: Metabolism
Uniprot ID: Q8IZQ1
