anti- WT1 antibody

Product Description

anti- WT1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA..

Immunogen: Wilms tumor 1

Synonyms: GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT 2, WT1, WT33

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF, IP

Recommended dilution: WB: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200; IP: 1:500-1:5000

Image 1: Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab09528 (WT1 antibody) at dilution of 1:200

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Image 4: A549 cells were subjected to SDS PAGE followed by western blot with FNab09528(WT1 antibody) at dilution of 1:1000

Gene ID: 7490

Research Area: Metabolism

Uniprot ID: P19544