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Product Description
anti- WWP1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF..
Immunogen: WW domain containing E3 ubiquitin protein ligase 1
Synonyms: AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IP
Recommended dilution: WB: 1:200-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
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Image 4: PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09534(WWP1 antibody) at dilution of 1:300
Gene ID: 11059
Research Area: Metabolism
Uniprot ID: Q9H0M0
