anti- WWP2 antibody

Product Description

anti- WWP2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells(ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation..

Immunogen: WW domain containing E3 ubiquitin protein ligase 2

Synonyms: AIP2, WW domain containing protein 2, WWP2, WWp2 like

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:200-1:2000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab09535(WWP2 antibody) at dilution of 1:100

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Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab09535(WWP2 antibody) at dilution of 1:500

Gene ID: 11060

Research Area: Metabolism

Uniprot ID: O00308