anti- XRCC5/Ku80 antibody

Product Description

anti- XRCC5/Ku80 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity..

Immunogen: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

Synonyms: 86 kDa subunit of Ku antigen, CTC85, CTCBF, DNA repair protein XRCC5, FLJ39089, G22P2, KARP 1, KARP1, Ku80, Ku86, KUB2, NFIV, Nuclear factor IV, Thyroid lupus autoantigen, TLAA, XRCC5

Reactivity: Human

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab09555(XRCC5 antibody) at dilution of 1:100

Image 2: .

Image 3:

Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09555(XRCC5 antibody) at dilution of 1:1000

Gene ID: 7520

Research Area: Metabolism

Uniprot ID: P13010