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Product Description
anti- XRN1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA(By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma(OGS)..
Immunogen: 5'-3' exoribonuclease 1
Synonyms: 5 3 exoribonuclease 1, 5' 3' exoribonuclease 1, DKFZp434P0721, DKFZp686B22225, DKFZp686F19113, FLJ41903, SEP1, XRN1
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human heart slide using FNab09556(XRN1 Antibody) at dilution of 1:50
Image 2: .
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09556(XRN1 antibody) at dilution of 1:600
Gene ID: 54464
Research Area: Metabolism
Uniprot ID: Q8IZH2
