Product Description
anti- XRN2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Possesses 5'->3' exoribonuclease activity(By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II(RNAp II) transcription termination R-loops formed by G-rich pause sites(PubMed:21700224)..
Immunogen: 5'-3' exoribonuclease 2
Synonyms: XRN2, DHM1 like protein, DHP protein, 5' 3' exoribonuclease 2, 5 3 exoribonuclease 2
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution: WB: 1:200-1:1000
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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09557(XRN2 antibody) at dilution of 1:200
Gene ID: 22803
Research Area: Metabolism
Uniprot ID: Q9H0D6