Product Description
anti- YWHAB antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form(by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13..
Immunogen: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Synonyms: 14 3 3, 14 3 3 alpha, 14 3 3 protein beta/alpha, YWHAB
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC
Recommended dilution: IHC: 1:20-1:200
Image 1: Immunohistochemical of paraffin-embedded human colon cancer using FNab09575(YWHAB antibody) at dilution of 1:50
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Gene ID: 7529
Research Area: Metabolism
Uniprot ID: P31946