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Product Description
anti- ZAK antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized..
Immunogen: sterile alpha motif and leucine zipper containing kinase AZK
Synonyms: AZK, HCCS 4, MLK related kinase, MLK7, mlklak, MLT, MLTK, MRK, ZAK
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50
Image 1: Immunohistochemistry of paraffin-embedded human colon carcinoma slide using FNab09581( ZAK Antibody) at dilution of 1:50
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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09581(ZAK antibody) at dilution of 1:1000
Gene ID: 51776
Research Area: Metabolism
Uniprot ID: Q9NYL2
