Euro
British Pound
US Dollar
Product Description
anti- ZBP1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor(IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3(By similarity)..
Immunogen: Z-DNA binding protein 1
Synonyms: ZBP1, C20orf183, DLM1, Z DNA binding protein 1, DLM 1
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human liver cancer using FNab09586(ZBP1 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09586(ZBP1 antibody) at dilution of 1:400
Gene ID: 81030
Research Area: Metabolism
Uniprot ID: Q9H171
