anti- ZBTB38 antibody

Product Description

anti- ZBTB38 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements(5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner(PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites(CFS) stability in a RBBP6-and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication(PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons(By similarity)..

Immunogen: zinc finger and BTB domain containing 38

Synonyms: ZBTB38, FLJ31131, FLJ35036, CIBZ, FLJ22332

Reactivity: Human

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human testis using FNab09593(ZBTB38 antibody) at dilution of 1:50

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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09593(ZBTB38 antibody) at dilution of 1:1000

Gene ID: 253461

Research Area: Metabolism

Uniprot ID: Q8NAP3