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Product Description
anti- ZC3HC1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1(CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events..
Immunogen: zinc finger, C3HC-type containing 1
Synonyms: ZC3HC1, 1110054L24Rik, hNIPA, HSPC216, NIPA
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution: WB: 1:200-1:2000
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Image 4: mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab09608(ZC3HC1 antibody) at dilution of 1:500
Gene ID: 51530
Research Area: Metabolism
Uniprot ID: Q86WB0
